DNA Medication Passport

A DNA Medication Passport is created by NIFGO – Dutch Institute for Pharmacogenetic Research and is a fully personalized document based on your unique genetic profile. It shows which genes you carry and how these genes affect medication.

What is pharmacogenetics?
Pharmacogenetics examines the individual’s ability to break down medication in the liver. This is an important DNA test, as the capacity of each person is different for different medications. A slow conversion may lead to stacking and unpleasant or even dangerous side effects. A conversion that is too fast can make the drug insufficiently effective. Part of this capacity is hereditary and can be determined via this DNA test.

Scientific research
Research results show that patients whose medication is matched to their DNA suffer 30% less harmful side effects, according to an international team of scientists led by Leiden hospital LUMC, The Netherlands.

The role of your liver enzymes
Liver enzymes play a crucial role in the metabolism of a variety of substances, including food, alcohol, nutritional supplements, as well as medication. These enzymes are involved in breaking down (metabolizing) drugs into their components, which can then be eliminated from the body. The activity of these enzymes can affect the efficacy and toxicity of a drug. In addition, certain drugs can also induce or inhibit the activity of these enzymes, leading to changes in drug metabolism and elimination. Therefore, the presence of certain liver enzyme levels can affect the way drugs are metabolized and processed in the body, affecting their effectiveness and safety.

Ordering the DNA Medication Passport
For pharmacists, medical specialists and Functional Medicine practitioners, these important insights in your DNA can make a significant difference in how to optimally support you. You can order the DNA passport here. A DNA passport only needs to be created once in your lifetime. At DNA Care we can offer you a consultation to discuss the findings in depth.